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• Activity deltas table
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Motif ID: HOX{A4,D4}.p2

Z-value: 0.884

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_205161821	1.283	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr11_-_16380967	1.056	NM_001145819 NM_017508	SOX6	SRY (sex determining region Y)-box 6
chr11_+_5329313	0.778	NM_001004750	OR51B6	olfactory receptor, family 51, subfamily B, member 6
chr6_+_50894397	0.763	NM_003221	TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr5_-_168204430	0.753
chr2_+_182558795	0.696	NM_001080545	PPP1R1C	protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr12_+_53177789	0.671		NCKAP1L	NCK-associated protein 1-like
chr12_+_53177806	0.659		NCKAP1L	NCK-associated protein 1-like
chr3_-_57209319	0.658	NM_003865	HESX1	HESX homeobox 1
chr12_+_53177758	0.657	NM_005337	NCKAP1L	NCK-associated protein 1-like
chr17_-_36181927	0.629	NM_181539	KRT26	keratin 26
chr3_+_182900081	0.624		SOX2OT	SOX2 overlapping transcript (non-protein coding)
chr9_+_263025	0.624	NM_001190458 NM_001193536	DOCK8	dedicator of cytokinesis 8
chr6_-_32892705	0.622	NM_002120	HLA-DOB	major histocompatibility complex, class II, DO beta
chr12_+_58369392	0.620	NM_004731	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr13_-_19703371	0.601	NM_006783	GJB6	gap junction protein, beta 6, 30kDa
chr11_-_5178505	0.598	NM_001004760	OR51V1	olfactory receptor, family 51, subfamily V, member 1
chr1_-_114215768	0.596	NM_001193431 NM_012411 NM_015967	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr7_+_143423073	0.592	NM_001004135	OR2A12	olfactory receptor, family 2, subfamily A, member 12
chr11_+_71605466	0.574	NM_000803 NM_001113534 NM_001113535 NM_001113536	FOLR2	folate receptor 2 (fetal)
chr5_+_149131695	0.566	NM_001172699	PPARGC1B	peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr1_-_108032645	0.557	NM_001079874	VAV3	vav 3 guanine nucleotide exchange factor
chr3_-_115380539	0.548	NM_000796 NM_033663	DRD3	dopamine receptor D3
chrX_+_79562601	0.527	NM_152630	FAM46D	family with sequence similarity 46, member D
chrX_+_134482212	0.526	NM_182540	DDX26B	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chrX_-_19598912	0.523	NM_001184960	SH3KBP1	SH3-domain kinase binding protein 1
chr12_+_53178834	0.518	NM_001184976	NCKAP1L	NCK-associated protein 1-like
chr17_-_36165050	0.512	NM_181534	KRT25	keratin 25
chrX_+_37524250	0.507		CYBB	cytochrome b-245, beta polypeptide
chrX_-_123925343	0.502	NM_001163278 NM_001163279 NM_014253	ODZ1	odz, odd Oz/ten-m homolog 1(Drosophila)
chr12_-_10464308	0.491	NM_002261 NM_007333	KLRC3	killer cell lectin-like receptor subfamily C, member 3
chr6_-_27988152	0.489	NM_033057	OR2B2	olfactory receptor, family 2, subfamily B, member 2
chr7_+_1239078	0.483	NM_001080461	UNCX	UNC homeobox
chr7_+_143683365	0.468	NM_005435	ARHGEF5	Rho guanine nucleotide exchange factor (GEF) 5
chr10_+_68355797	0.467	NM_178011	LRRTM3	leucine rich repeat transmembrane neuronal 3
chr1_-_205272619	0.455	NM_001083924 NM_023938	C1orf116	chromosome 1 open reading frame 116
chr13_+_77007809	0.452	NM_001160706 NM_003843 NM_144777	SCEL	sciellin
chr22_+_21065134	0.448		LOC100290481	immunoglobulin lambda light chain-like
chrX_-_84521398	0.446	NM_024921	POF1B	premature ovarian failure, 1B
chrX_+_144710557	0.439	NM_001144006 NM_001144008 NM_001144009 NM_001144010	SLITRK2	SLIT and NTRK-like family, member 2
chr17_-_36779399	0.436	NM_002279	KRT33B	keratin 33B
chrX_+_37524190	0.434	NM_000397	CYBB	cytochrome b-245, beta polypeptide
chr6_+_132915522	0.434	NM_053278	TAAR8	trace amine associated receptor 8
chr7_-_143523582	0.432	NM_001003702	ARHGEF35	Rho guanine nucleotide exchange factor (GEF) 35
chrX_-_84521320	0.422		POF1B	premature ovarian failure, 1B
chr7_-_143622188	0.421		ARHGEF5	Rho guanine nucleotide exchange factor (GEF) 5
chr17_-_36276987	0.421	NM_000223	KRT12	keratin 12
chr5_+_140481763	0.419	NM_018938	PCDHB4	protocadherin beta 4
chr4_-_47678187	0.419	NM_001142564	CNGA1	cyclic nucleotide gated channel alpha 1
chr6_-_116973465	0.415	NM_001139444	BET3L	BET3 like (S. cerevisiae)
chr6_+_50789215	0.414	NM_172238	TFAP2D	transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr11_-_119514058	0.414	NM_012101	TRIM29	tripartite motif containing 29
chr6_+_32713160	0.413	NM_002122	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr3_+_1109619	0.409	NM_014461	CNTN6	contactin 6
chrX_+_109548940	0.402	NM_020769	RGAG1	retrotransposon gag domain containing 1
chr10_+_118177371	0.393	NM_001011709	PNLIPRP3	pancreatic lipase-related protein 3
chr5_-_56814310	0.388	NM_001017992	ACTBL2	actin, beta-like 2
chr20_-_30703219	0.376	NM_182584	C20orf203	chromosome 20 open reading frame 203
chr1_+_159943385	0.376	NM_001184866 NM_001184867 NM_001184870 NM_001184871 NM_001184872 NM_001184873 NM_032738	FCRLA	Fc receptor-like A
chr10_+_91051685	0.374	NM_001547	IFIT2	interferon-induced protein with tetratricopeptide repeats 2
chrX_+_65152004	0.366
chr12_-_51086330	0.361	NM_033033	KRT82	keratin 82
chr15_-_19007127	0.360	NM_001145004	GOLGA6L6	golgin A6 family-like 6
chr1_+_158426908	0.355	NM_001231	CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)
chr17_-_8711701	0.354	NM_001010855	PIK3R6	phosphoinositide-3-kinase, regulatory subunit 6
chr12_+_111713931	0.352	NM_001143854 NM_014954	RPH3A	rabphilin 3A homolog (mouse)
chr3_+_2528272	0.352		CNTN4	contactin 4
chr1_+_65503011	0.350	NM_014787	DNAJC6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr13_+_42034871	0.349	NM_033012	TNFSF11	tumor necrosis factor (ligand) superfamily, member 11
chrX_-_15312390	0.344	NM_004469	FIGF	c-fos induced growth factor (vascular endothelial growth factor D)
chr1_-_158883666	0.339	NM_003037	SLAMF1	signaling lymphocytic activation molecule family member 1
chr8_-_87824996	0.336	NM_019098	CNGB3	cyclic nucleotide gated channel beta 3
chr18_-_68683913	0.336	NM_138999 NM_153181	NETO1	neuropilin (NRP) and tolloid (TLL)-like 1
chr8_+_11388918	0.335	NM_001715	BLK	B lymphoid tyrosine kinase
chr3_+_160269836	0.335		IQCJ	IQ motif containing J
chr19_+_54128750	0.335	NM_014475	DHDH	dihydrodiol dehydrogenase (dimeric)
chr11_-_13474101	0.334	NM_000315	PTH	parathyroid hormone
chr7_+_106897737	0.331	NM_005295	GPR22	G protein-coupled receptor 22
chr12_-_92001543	0.327		RPL41P5	ribosomal protein L41 pseudogene 5
chr2_+_113542017	0.326	NM_173161	IL1F10	interleukin 1 family, member 10 (theta)
chr6_+_105511615	0.321	NM_001004317	LIN28B	lin-28 homolog B (C. elegans)
chr2_-_113526910	0.317	NM_014438 NM_173178	IL1F8	interleukin 1 family, member 8 (eta)
chrX_-_131401319	0.316	NM_018388 NM_133486	MBNL3	muscleblind-like 3 (Drosophila)
chr4_-_151990061	0.315		LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chr2_-_215605054	0.312	NM_015657	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr2_-_70634129	0.310	NM_001099691 NM_003236	TGFA	transforming growth factor, alpha
chr11_-_5110383	0.310	NM_001005160	OR52A5	olfactory receptor, family 52, subfamily A, member 5
chr4_+_119174947	0.307	NM_004784	NDST3	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr2_+_172530120	0.306		HAT1	histone acetyltransferase 1
chr18_+_27210737	0.305	NM_001134453 NM_177986	DSG4	desmoglein 4
chr4_-_123761615	0.304	NM_021803	IL21	interleukin 21
chr19_+_14554895	0.302	NM_207390	CLEC17A	C-type lectin domain family 17, member A
chr15_+_88545510	0.302	NM_198925	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr12_+_47205681	0.301	NM_001005203	OR8S1	olfactory receptor, family 8, subfamily S, member 1
chr11_-_117589283	0.301	NM_153206	AMICA1	adhesion molecule, interacts with CXADR antigen 1
chr9_+_126460511	0.298
chr12_-_7793335	0.297	NM_130441 NM_203503	CLEC4C	C-type lectin domain family 4, member C
chr4_-_38710376	0.295	NM_024943	TMEM156	transmembrane protein 156
chrX_+_134482387	0.295		DDX26B	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr12_-_101398429	0.294		IGF1	insulin-like growth factor 1 (somatomedin C)
chr11_+_5466490	0.294	NM_001005163	OR52D1	olfactory receptor, family 52, subfamily D, member 1
chr10_-_69095362	0.291	NM_001127384	CTNNA3	catenin (cadherin-associated protein), alpha 3
chrX_-_11194015	0.290	NM_013423	ARHGAP6	Rho GTPase activating protein 6
chr13_-_83354474	0.289	NM_052910	SLITRK1	SLIT and NTRK-like family, member 1
chr1_+_207668787	0.288	NM_001104548	LOC642587	NPC-A-5
chr19_-_7672978	0.287	NM_002002	FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)
chr5_-_95044415	0.286	NM_031952	SPATA9	spermatogenesis associated 9
chrX_+_12795111	0.284	NM_016562	TLR7	toll-like receptor 7
chr11_+_5925152	0.284	NM_001003443	OR56A3	olfactory receptor, family 56, subfamily A, member 3
chr16_-_56562512	0.282	NM_001135639 NM_001297	CNGB1	cyclic nucleotide gated channel beta 1
chr6_+_154449334	0.279	NM_001145287	OPRM1	opioid receptor, mu 1
chr15_+_38319326	0.279	NM_020168	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr11_+_4466684	0.278	NM_001005171	OR52K1	olfactory receptor, family 52, subfamily K, member 1
chr2_+_79593679	0.277		CTNNA2	catenin (cadherin-associated protein), alpha 2
chr5_-_147142444	0.277	NM_014790	JAKMIP2	janus kinase and microtubule interacting protein 2
chr3_+_99288706	0.277	NM_054106	OR5AC2	olfactory receptor, family 5, subfamily AC, member 2
chrX_+_99726445	0.276	NM_022144	TNMD	tenomodulin
chr11_+_59979857	0.275	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr19_+_55965532	0.274	NM_001506	GPR32	G protein-coupled receptor 32
chr5_+_176494690	0.271		NSD1	nuclear receptor binding SET domain protein 1
chr6_+_28032997	0.271	NM_012367	OR2B6	olfactory receptor, family 2, subfamily B, member 6
chr4_+_71298187	0.269	NM_021225	PROL1	proline rich, lacrimal 1
chr2_+_17861266	0.265	NM_001105569	MSGN1	mesogenin 1
chr1_+_559618	0.263
chr4_+_71235259	0.262	NM_033122	CABS1	calcium-binding protein, spermatid-specific 1
chr2_+_225973845	0.262	NM_020864	KIAA1486	KIAA1486
chr7_+_128293699	0.261	NM_001195150	LOC100130705	hypothetical protein LOC100130705
chr1_+_556968	0.260
chrX_+_92815667	0.260	NM_001171109 NM_001171110 NM_001171111 NM_173698	FAM133A	family with sequence similarity 133, member A
chr18_+_59295123	0.259	NM_002639	SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr5_-_14706486	0.258
chr12_-_7547552	0.258	NM_004244 NM_203416	CD163	CD163 molecule
chr1_+_159959072	0.257	NM_001002901	FCRLB	Fc receptor-like B
chr1_-_203579932	0.257		KLHDC8A	kelch domain containing 8A
chr1_+_559129	0.256
chr1_+_198263352	0.255	NM_003822 NM_205860	NR5A2	nuclear receptor subfamily 5, group A, member 2
chr3_-_74652952	0.255	NM_020872	CNTN3	contactin 3 (plasmacytoma associated)
chr10_-_105835609	0.254	NM_000494	COL17A1	collagen, type XVII, alpha 1
chr4_+_70928718	0.253	NM_000200	HTN3	histatin 3
chrX_-_137649180	0.253	NM_033642	FGF13	fibroblast growth factor 13
chr17_-_3408038	0.253	NM_145068	TRPV3	transient receptor potential cation channel, subfamily V, member 3
chr1_-_42738535	0.251		TMSB4XP1	thymosin beta 4, X-linked pseudogene 1
chr5_-_147142457	0.251		JAKMIP2	janus kinase and microtubule interacting protein 2
chr3_-_191322919	0.251	NM_001134418	LEPREL1	leprecan-like 1
chr1_-_150029529	0.248	NM_001083963 NM_001083964 NM_001083965 NM_006862	TDRKH	tudor and KH domain containing
chr12_-_54150188	0.247	NM_001005499	OR6C70	olfactory receptor, family 6, subfamily C, member 70
chr9_+_74326536	0.247	NM_138691	TMC1	transmembrane channel-like 1
chr4_-_64957595	0.246	NM_001010874	TECRL	trans-2,3-enoyl-CoA reductase-like
chr4_-_40212670	0.246	NM_019027	RBM47	RNA binding motif protein 47
chr18_+_59705918	0.244	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr7_+_116447499	0.244		ST7	suppression of tumorigenicity 7
chr1_-_158815850	0.244		CD84	CD84 molecule
chr21_-_30460841	0.244	NM_012131	CLDN17	claudin 17
chr14_-_104602784	0.243	NM_013345	GPR132	G protein-coupled receptor 132
chr1_-_158759606	0.243	NM_001184714 NM_001184715 NM_001184716 NM_052931	SLAMF6	SLAM family member 6
chr7_+_141457977	0.241		LOC93432	maltase-glucoamylase-like pseudogene
chr5_-_147142249	0.241		JAKMIP2	janus kinase and microtubule interacting protein 2
chr1_+_938709	0.241	NM_005101	ISG15	ISG15 ubiquitin-like modifier
chr9_+_92629525	0.240	NM_001174167	SYK	spleen tyrosine kinase
chr9_+_86474445	0.240	NM_001007097	NTRK2	neurotrophic tyrosine kinase, receptor, type 2
chr11_-_119514011	0.239		TRIM29	tripartite motif containing 29
chr13_-_83354425	0.238		SLITRK1	SLIT and NTRK-like family, member 1
chr17_+_51585834	0.235	NM_153228	ANKFN1	ankyrin-repeat and fibronectin type III domain containing 1
chr10_+_129237602	0.235	NM_001030013	NPS	neuropeptide S
chr11_-_5037432	0.231	NM_001005164	OR52E2	olfactory receptor, family 52, subfamily E, member 2
chr14_-_104602809	0.231		GPR132	G protein-coupled receptor 132
chr19_-_47623340	0.231	NM_005357	LIPE	lipase, hormone-sensitive
chr1_-_156923111	0.229	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_+_142590633	0.228	NM_176881	TAS2R39	taste receptor, type 2, member 39
chr7_-_138014329	0.228	NM_001139456	SVOPL	SVOP-like
chr8_+_19840861	0.228	NM_000237	LPL	lipoprotein lipase
chr7_-_143622233	0.225		ARHGEF35	Rho guanine nucleotide exchange factor (GEF) 35
chr10_-_123343320	0.225	NM_001144913 NM_001144914	FGFR2	fibroblast growth factor receptor 2
chr4_+_71492581	0.223	NM_016519	AMBN	ameloblastin (enamel matrix protein)
chr1_-_167947301	0.223	NM_000655	SELL	selectin L
chr1_+_40631603	0.221	NM_001198979	SMAP2	small ArfGAP2
chr12_-_101398470	0.221		IGF1	insulin-like growth factor 1 (somatomedin C)
chr5_+_69356827	0.220	NM_001178087 NM_022978 NM_021967 NM_022968	SERF1B SERF1A	small EDRK-rich factor 1B (centromeric) small EDRK-rich factor 1A (telomeric)
chr19_-_20399601	0.220		ZNF826P	zinc finger protein 826, pseudogene
chr1_-_34404029	0.219	NM_052896	CSMD2	CUB and Sushi multiple domains 2
chr19_-_55560686	0.218	NM_004851	NAPSA	napsin A aspartic peptidase
chr12_-_11030777	0.218	NM_176890	TAS2R50	taste receptor, type 2, member 50
chr14_+_19458580	0.218	NM_001005483	OR4K5	olfactory receptor, family 4, subfamily K, member 5
chr16_+_56286212	0.218	NM_032269	CCDC135	coiled-coil domain containing 135
chr17_-_36209672	0.217	NM_181535	KRT28	keratin 28
chr4_-_72868598	0.216	NM_000583	GC	group-specific component (vitamin D binding protein)
chr15_-_70838703	0.216
chr12_-_52016270	0.216	NM_001173467	SP7	Sp7 transcription factor
chr11_-_102250876	0.216	NM_002426	MMP12	matrix metallopeptidase 12 (macrophage elastase)
chr4_-_74704964	0.215	NM_177532 NM_201431	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr3_-_18455207	0.215	NM_001131010	SATB1	SATB homeobox 1
chr7_+_128802719	0.215	NM_001130722	AHCYL2	adenosylhomocysteinase-like 2
chr1_-_149004852	0.214		CTSS	cathepsin S
chr2_-_158008763	0.214	NM_004288	CYTIP	cytohesin 1 interacting protein
chr11_+_125163215	0.214	NM_001129883	PATE3	prostate and testis expressed 3
chr2_+_113591940	0.213	NM_000577 NM_173841 NM_173843	IL1RN	interleukin 1 receptor antagonist
chr14_-_56342097	0.212	NM_172337	OTX2	orthodenticle homeobox 2
chr13_-_46368968	0.212	NM_000621 NM_001165947	HTR2A	5-hydroxytryptamine (serotonin) receptor 2A
chr19_+_17723285	0.212	NM_001161359 NM_015122	FCHO1	FCH domain only 1
chrX_-_114158388	0.211	NM_000640	IL13RA2	interleukin 13 receptor, alpha 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.98	2.77e-07	GO:0007606	sensory perception of chemical stimulus
1.68	1.57e-06	GO:0007600	sensory perception
1.92	1.87e-05	GO:0007608	sensory perception of smell
1.17	4.52e-03	GO:0032501	multicellular organismal process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.19	7.93e-04	GO:0005886	plasma membrane
1.19	8.71e-04	GO:0071944	cell periphery
1.27	6.33e-03	GO:0005576	extracellular region
1.14	1.94e-02	GO:0031224	intrinsic to membrane
1.13	3.87e-02	GO:0016021	integral to membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.51	1.66e-09	GO:0004872	receptor activity
1.69	9.43e-08	GO:0004930	G-protein coupled receptor activity
1.41	1.22e-07	GO:0004871	signal transducer activity
1.41	1.22e-07	GO:0060089	molecular transducer activity
1.52	6.37e-07	GO:0004888	transmembrane receptor activity
1.94	5.84e-06	GO:0004984	olfactory receptor activity